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This study randomized 808 previously untreated HER2-positive MBC patients to pertuzumab with trastuzumab and docetaxel or placebo with trastuzumab and docetaxel ().
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Among women for whom the interval between the initial diagnosis of disease and the diagnosis of metastatic disease was 3 months to less than 5 years, the rate of prior receipt of tamoxifen therapy was 47%; among women for whom the interval was 5 years to less than 10 years, the rate was 23%; and among women for whom the interval was 10 years or more, the rate was 38%.
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Disclosures: Dr. Wasfy reports grants from the National Institutes of Health during the conduct of the study.
There were more deaths related to breast cancer in the tamoxifen than in the Arimidex treatment group.
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Many studies indicate that one of the primary benefits of testosterone therapy is the prevention of bone loss.
SOURCE: Washington University in St. Louis, news release, Feb.
These include osteoblasts and chondrocytes in bone, stromal cells of fat, Leydig and germ cells of testes (in males), smooth muscle cells of the vasculature, and several areas of the hypothalamus, limbic system, and cerebral cortex.
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As opposed to the wellknown histories of the Tuskegee Syphilis experiments and Nazi eugenics that emphasize exceptional episodes in the history of medicine, an examination of early racial medicine and its infestation of medical schools draws attention to many unexceptional and largely unquestioned aspects of race in medical practice.
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